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Moreover, phospho-BCL-XL (Ser62) stabilizes G2 arrest by binding to and co-localizing with Cdk1 (cdc2) in nucleolar structures to avoid rapid nucleolar disassembly associated with mitosis onset, playing an unexpected role in the G2 phase checkpoint downstream of DNA damage distinct from its anti-apoptotic function 22

12,205,206,207 In line with that NAD + -capped RNA levels respond to the cellular total NAD + concentrations, the capping efficiencies of NAD + capping and NADH capping are also regulated by intracellular NAD + /NADH ratio

Increased ROS levels are involved in many pathological conditions and diseases, including cardiovascular disease, diabetes, aging and cancer [3,4,5]