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Targeting lipid GPCRs to treat type 2 diabetes mellitus - progress and challenges

Lower levels of these strains shift the balance of beneficial bacteria in the gut in ways that can increase histamine burden and reduce the gut's capacity to regulate immune signaling

doi: 10.1158/1541-7786.MCR-05-0261 84 SotoAMSonnenscheinC

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However, it is consistent with other studies, so it warrants further study to better understand the biological mechanisms. Public health implications The researchers acknowledged study limitations, including the potential for confounding in observational studies and the fact that several cancer types in the analysis had low event rates, leading to wide confidence intervals and limiting statistical power

Journal of Integrative Medicine