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Choudhary, D., Bhattacharyya, S., & Bose, S

Today, several GLP-1 RAs are available in the market

Rare heterozygous loss-of-function variants in the human GLP-1 receptor do not associate with cardiometabolic phenotypes

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Alternative RNA processing in calcitonin gene expression generates mRNAs encoding different polypeptide products

Researchers also examined major adverse CV events in patient subgroups on the basis of major adverse CV event rates in the placebo group, the presence or absence of CVD, HbA1c level, trial duration, treatment dosing interval, structural homology to human GLP-1 or exendin-4, BMI, age and eGFR