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Norfolk Plant Sciences About Norfolk Plant Sciences Archived March 4, 2016, at the Wayback Machine Clive Cookson for the Financial Times

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C57BL/6 male mice, 28 months of age, treated with GHK at a dose of 10 mg/kg body weight 5 times per week for 3 weeks showed improved learning compared to saline treated control mice

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The effective dose is determined by CNS receptor saturation and blood-brain barrier kinetics, not by volume of distribution or total body mass