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Expert Opinion on Biological Therapy 12(1):37-51

For example, EA was conjugated to 2-amino-2-deoxy-d-glucose (EAG) 90 , obtaining an adduct with significant anticancer activity such as EA but without the undesired diuretic activity 90

Mitochondrial glutathione is particularly critical for protecting against oxidative damage, as mitochondria lack the enzymes for glutathione synthesis and must import it from the cytosol via specific transport systems

Spermidine synthase is encoded by the SRM gene (also known as SPDSY) which is located on chromosome 1p36.22 and is composed of 8 exons that encode a protein of 302 amino acids

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