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For patients with severe obesity (BMI 40 or 35 with obesity-related complications), referral for evaluation of bariatric surgery may be appropriate according to American Society for Metabolic and Bariatric Surgery guidelines
Some analgesics interact with GLP-1 medications or may worsen nausea when combined with tirzepatide
The most evidence-supported approach to muscle preservation is dietary protein not supplements
Clifford J
All these methods aim to make the waist area look better from every angle
Phase 2 results (48 weeks): 1mg dose: 8.7% average weight loss 4mg dose: 17.1% average weight loss 8mg dose: 22.8% average weight loss 12mg dose: 24.2% average weight loss Placebo: 2.1% average weight loss These numbers came from a 48-week study period, six months shorter than the 72-week SURMOUNT trials
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