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That is worth saying plainly, because the same review this page cites (Urbina 2026) found thiamine and cobalamin deficits increase over time on GLP-1 therapy, and that in patients with rapid weight loss, persistent vomiting, or very poor oral intake, suspected thiamine deficiency is a medical urgency

JAMA 323(12):11751183

In total, 5 studies included patients with T2DM (2427, 29) while another 6 studies evaluated patients with overweight or obesity without T2DM (10, 28, 30, 31, 33, 34)

Consume 15 grams of fast-acting carbohydrates, such as 4 glucose tablets, half a cup of juice, or a tablespoon of honey

This offers an additional large potential revenue stream IF IND application is successful AND additional clinical trials show significant benefits