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AhR activation by kynurenic acid leads to anti-inflammatory effects, which are beneficial in reducing vascular inflammation (114)

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DOI:10.1074/mcp.M110.006924 52

This imbalance contributes to the increased permeability of the gut barrier, allowing the translocation of harmful bacterial products (such as lipopolysaccharides (LPS)) into the bloodstream, where they can activate the brains immune system and promote neuroinflammation, which is a major contributor to cognitive dysfunction (Guerville and Boudry, 2016

Cellular imaging studies were supported by Fondation pour la recherche sur le Cerveau, FRC Espoir en tte

Is It Safe to Take Glutathione While Pregnant