Unsupervised graph-based clustering was performed on the first 20 principal components
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The four subclasses of IgG [1,2,3,4] have differing capacities to engage FcRn and other immune effector molecules [129, 130], and which subclass that drives pathology differs across autoimmune diseases
Competing Interests The authors declare that they have no competing interests Materials and Methods Plasmid construction Amino acids mutations to switch Rex-domain specificity from NAD to NADP were selected based on a previous screen [15]
Most patients notice: Less pain and stiffness over the first 1 to 3 months
Jul 2018;6(3):446-456