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* **Gradual Dose Reduction When Discontinuing Therapy:** To prevent withdrawal symptoms such as insomnia, irritability, or rebound anxiety, tapering the dose rather than abrupt cessation is advisable

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Furthermore, oral formulations may enhance convenience, acceptance, and adherence to GLP-1RA therapy, offering an alternative to facilitate the attainment of glycemic targets, especially in patients hesitant to commence injectable medications [49]

Preparation, assay, and partial purification of a thymic lymphocytopoietic factor (thymosin)

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Patients already on metformin HCl (N=431) at a dose of at least 1,500 mg per day were randomized after completing a 2-week single-blind placebo run-in period