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For these reasons, it is believed that in AD, GLP-1 reduces neuronal apoptosis, neuroinflammation, and the typical gliosis

The microvascular dysfunction typically seen in patients with DM [56] may have direct adverse effects on skeletal muscle

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Additionally, there was some heterogeneity in follow-up durations across the trials, ranging from week 52 to 72

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The table below compares all 12 options by mechanism, typical weight loss, form, and whether insurance generally covers them for weight loss or diabetes indications