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GLP-1 RAs and SGLT-2 inhibitors both have beneficial weight effects that should inform drug selection

Despite the similarly large decreases in body weight, the Sema group showed significant lean mass loss compared to the control group during the 4-week treatment period, while the Sema + -MSTN/-ActA group was not only protected against this lean mass loss, but also had a significant increase in lean mass (Fig

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In a study published in JAMA Psychiatry in February 2025 that included 48 patients with AUD, researchers found low-dose weekly injections of semaglutide significantly reduced alcohol cravings and nicotine use compared with placebo