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[DOI] [PMC free article] [PubMed] [Google Scholar] 474.DAntonio, L

In contrast, mitochondrial PRDX3 undergoes hyperoxidation during lipid peroxidation stress and translocates to the plasma membrane, where it suppresses cystine uptake, depletes intracellular GSH, and amplifies ferroptotic execution 114

Overall, GSH helps preserve membrane function

Bull World Health Organ 82(5):346353 Dickinson DA, Forman HJ (2002) Glutathione in defence and signaling: lesson from a small thiol

& Chow, J

Despite the relatively high incidence, there is no FDA approved medical therapy for ASD at this time to address the core symptoms or the pathophysiological processes of this condition