GLP-1 RA therapy significantly reduced CRP levels compared to placebo (SMD = -0.59
Its also approved to reduce the risk of serious cardiovascular events, like heart attack or stroke, in adults with both type 2 diabetes and heart disease
The landmark SUSTAIN trials (1-7) and STEP trials (1-4) all used once-weekly dosing and demonstrated sustained weight loss, improved blood sugar control, and cardiovascular benefits
How quickly does dietary GLP-1 activation affect hunger signals
Taking your dose a day early might not worsen these side effects, but monitoring how you feel is important
SGLT-2 inhibitors, such as empagliflozin, canagliflozin and dapagliflozin, are considered to have intermediate efficacy for glycemic control, and are associated with weight loss and a low risk of hypoglycemia [6]