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Stress lowers SCFA production, disrupts gut barrier and intestinal lining health , weakens GLP-1 signaling, and increases inflammatory species, all of which intensify hunger and cravings

Topiramate increases kidney stone risk, and adequate fluid intake is the simplest protective measure

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2 These medications, while effective for weight loss, have been associated with unintended effects on facial appearance, often referred to as Ozempic face. Patients taking GLP-1 RAs may experience rapid or massive weight loss (MWL), whereas patients using lifestyle modifications for weight loss may experience gradual, less pronounced weight loss

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Varli M, Turhan S, Aras S, Atli T, Erdogan G