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The figure shows a significant increase in the volume of searches for Ozempic in the United States from July 2019 to July 2024, peaking around mid-2023

Eating disorder risk For individuals with a history of disordered eating, GLP-1-induced appetite suppression can unintentionally reinforce restriction or trigger old patterns

ClinicalTrials.gov (2017)

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5-7 Multiple studies have linked gut dysbiosis a change or imbalance in the diversity, composition and functions of the microbiota to reduced GLP-1 levels

Gut peptide hormones such as GLP-1 could potentially also have an impact on appetite regulation by effects on gastric emptying and direct CNS effects, but we needed a robust methodology that could be used to measure acute effect of putative hormones on subjective appetite and spontaneous food intake