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While age certainly contributes to the maturation of dry and wrinkled skin, it's not the main offender

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It declines with age, and lower NAD+ is associated with slower metabolism and the changes we lump together as getting older. NNMT, meanwhile, consumes the raw materials your body uses to make NAD+ and in fat tissue, NNMT is often overexpressed, which can drag NAD+ down right where you least want a sluggish metabolism

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Glutathione-SR provides the direct substrate necessary for Glutathione S-transferases (GSTs) to perform their vital conjugation work