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However, she remained determined, and when she was introduced to semaglutide, it became her turning point

Alivernini S, Firestein GS, McInnes IB

however, in the GLP-1 landscape, the trade-off is complex : a daily oral dose for ease of use versus a weekly subcutaneous autoinjection with superior weight-loss efficacy

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Based on these findings, we propose an intrinsic agonist model of the ECD for GLP-1R activation, in which the ECD is the major determining factor in activation of GLP-1R (Figure 9)

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