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Some patients may experience increased appetite or weight regain after stopping treatment

Spironolactone can commonly cause side effects such as stomach pain, vomiting, diarrhea, enlarged breasts (in men or women), irregular periods, erection problems, increased hair growth, and high potassium levels

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Weight and hormones are deeply connected, so patients who also optimize testosterone or estrogen and progesterone where appropriate often see better body composition changes than those on medication alone

1 Lilly also reduced the price of the 2.5 mg and 5 mg vials