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One type of mutation, found almost exclusively in people of Ashkenazi Jewish heritage, affects the autonomic and sensory nervous system development causing familial dysautonomia (FD ) Another mutation causes an increased level of phenylalanine (Phe) in the bloodstream resulting in a metabolic disorder called phenylketonuria (PKU)

doi: 10.31202/ecjse.963670 215

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For a detailed comparison of these secretagogues, see Ipamorelin vs CJC-1295