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( Differently, studies conducted in women with PCOS treated with DPP4is have shown a decrease in inflammatory cytokine expression and oxidative stress, and activation of the anti-apoptotic pathway, thus improving ovarian cycles and ovulation ( In summary, although the studies on this topic are scarce, a direct or indirect beneficial impact of DPP4is, even if mild, on testis function cannot be ruled out

Keeping a symptom journal and noting the timing of any GI disturbances helps clinicians determine whether semaglutide itself is triggering problems or whether other factors are at play

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Archives of Medical Research, 34 (1), 5055

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