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Glycine -methyltransferase deletion in mice diverts carbon flux from gluconeogenesis to pathways that utilize excess methionine cycle intermediates

Pfeffer MA, Claggett B, Diaz R, ELIXA Investigators, et al

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To investigate cognitive and affective symptoms, we analyzed the striatum, thalamus, medial prefrontal cortex (mPFC), and cerebellum, regions involved in motor, executive, and emotional functions ( Figure 4A )

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