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Follow-up and outcomes Histopathologic examination of the excised tissue revealed the characteristic biphasic pattern of cell distribution: (1) smaller round cells with scanty cytoplasm and hyperchromatic nuclei in a fibrillary & vascularized fibrocollagenous background (Fig

The clinical and biochemical features of the 3 patients reported here demonstrate that at least certain BBOX1 variants cause a significant phenotype affecting neuromuscular and psycho-mental development and functioning

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Their mechanism involves enhanced insulin release, delayed gastric emptying through reduced antral and duodenal motility with increased pyloric tone, and appetite suppression mediated via central nervous system pathways [4]