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Less common adverse effects observed in clinical trials include transient increases in heart rate, typically modest and not associated with adverse cardiovascular events in trial populations

L Carnitin 60 180 ( 10 12 )

DOI: [ Links ] 12

However, the use of reliable and robust mathematical models with predictive capabilities, known as the quantitative pharmacology approach (QP-A) and model-based drug development (MBDD), holds promise as a supportive strategy