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The co-culture findings contrasted findings from monoculture microglial system where an opposite pattern of oxysterol production was observed highlighting the importance of cellular interactions within the brain microenvironment in regulating oxysterol metabolism

Similarly, chitin, derived from N -acetylglucosamine [137], blocks the recognition of C

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In a follow up study 18 months later, creatine continued to show efficacy as a neuroprotective agent (Investigators, 2008) and it is currently in Phase III trials (NET-PDLS 2 )

174 Additionally, costunolide, a sesquiterpene lactone, improved microbial diversity and intestinal permeability in IBS models

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