Wegovy (semaglutide), an injection that is FDA approved for weight loss rather than managing blood sugar levels, contains the same active ingredient as Ozempic
What it revealed: He had low testosterone
A 2024 meta-analysis of 17 studies (402 UC and 362 CD) [70] showed that the percentage of circulating Treg cells was significantly reduced and the inhibitory function of circulating Treg cells was impaired in patients with active IBD and healthy controls, and the proportion of Treg cells in the inflammatory area of the intestine was higher than that in the non-inflammatory area
"The new class of weight-loss drugs that includes Wegovy and Zepbound work like the gastrointestinal hormones that naturally exist in our body
Through TR expressed in HSCs, TH facilitates the reversion of activated myofibroblasts to a quiescent phenotype, promotes apoptotic clearance, and inhibits fibrogenic gene expression (96)
Some report improved sleep quality or subtle increases in energy, though these could reflect placebo effects
