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DNA repair : NAD+ is involved in repairing damaged DNA, helping maintain our genetic codes integrity

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Furthermore, in snapshots around 320450 ns, the upper half of helix I moves together with the ECD away from the orthosteric pocket of the TMD, providing enough space for binding of the GLP-1s C-terminus to the ECD as well as docking of the N-terminus of GLP-1 to the orthosteric pocket in the TMD

IGF-1 LR3 activates IGF1R with high affinity and can activate hybrid IGF1R/IR receptors to some degree