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After five years of follow-up in patients with T2DM, the GLP-1 RAs and SGLT-2 inhibitors groups demonstrated significant reductions in mortality, CHD, HF, AF, stroke, peripheral vascular disease, and CKD, regardless which one of the drugs or its combination were used

10.1038/ncb1301 Am J Cardiovasc Dis

In its Phase 3 TRIUMPH-1 trial, patients on the top dose lost about 28 percent of their body weight over 80 weeks, the highest figure this class has produced

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