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The first-order dissociation reaction rate constant for RT-GSH is 20.3 10 3 s 1 , which is more than 500 times faster than that for ThiolQuant Green-GSH (35.7 10 6 s 1 )

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Participants received tirzepatide or placebo for 72 weeks (Jastreboff et al., NEJM 2022)

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T2D adults seeking blood sugar control T2D adults whose clinician selects tirzepatide over semaglutide for mechanism reasons Adults seeking tirzepatide-based weight management who specifically prefer the Mounjaro brand Mounjaro is FDA-approved for type 2 diabetes, not for weight loss

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