Network construction and analysis algorithms, such as weighted gene co-expression network analysis (WGCNA), are used to identify gene network modules and key genes, while Protein-protein Interaction (PPI) network analysis algorithms construct networks based on protein interaction information, and MCODE is used to identify dense subgraphs within networks
10 , eaar4338 (2018)
I discussed #2 in the NOTW
Preserving lean muscle mass Improving insulin sensitivity Supporting cardiovascular and mental health Sagging skin Muscle loss Fatigue or lowered metabolic rate Visual Snapshot : GLP-1 weight-loss treatments , fitness guidance, and body-contouring strategies to support healthier and more sustainable results
Curcumin (Turmeric): A Direct GLP-1 Secretagogue Curcumin the active compound in turmeric functions as a direct GLP-1 secretagogue, meaning it stimulates L-cells to release GLP-1
Other proposed contributors discussed in the literature include modulation of the dopaminergic and serotonergic systems, growth hormone receptor expression in fibroblasts, and interaction with the nitric oxide system at the level of vasomotor regulation (Sikiric et al., 2018)