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A knockdown study and a small-molecule mouse study are exactly the steps that should precede a human trial, and they are the reason a compound gets taken seriously enough to be studied further

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[DOI] [PMC free article] [PubMed] [Google Scholar] 173.Matsuo M., Sakakibara T., Sakiyama Y., So T., Kosuga M., Kakiuchi T., Ichinose F., Nakamura T., Ishitsuka Y., Irie T