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Injected directly into affected areas, it restores lubrication , cushions worn tissues , and reduces inflammation , making it a go-to for knee osteoarthritis, general joint pain, and back conditions like facet joint arthritis

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Marketed in the United States, DPP4i has also been evaluated for cardiovascular safety in large cardiovascular outcome trials (CVOTs) and neither type of DPP4i increases the risk of major adverse cardiovascular events [72,76]

Whether tirzepatide or retatrutide proves to be the optimal choice for a given individual will depend on factors that continue to clarify as clinical evidence accumulates

A collagen diet is relatively safe if carefully monitored