Regular physical activity promotes healthy weight management
Side effect tolerability edge: semaglutide (slight) Both drugs have similar side effect profiles overall
Compared with insulin degludec or glargine, tirzepatide lowers blood sugar with less risk of hypoglycemia in many patients because it increases insulin secretion only when glucose levels rise
Some people lose their appetite and eat less, but many experience increased cravings for high-calorie comfort foods
The overall incidence of AEs was similar between oral semaglutide and comparators (approximately 6080% of patients in any subgroup had an AE) and, as expected, gastrointestinal AEs (primarily nausea, vomiting and diarrhoea) made up a substantial proportion of the overall events for oral semaglutide
Ipamorelin: the first selective growth-hormone secretagogue, characterizing GHS-R1a binding and GH release