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2.2.2 T cells T follicular helper (T FH ) cells display distinct lipid metabolic profiles, characterized by the localization of phosphatidylethanolamine predominantly on the outer plasma membrane

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Peptides are short chains of amino acids that act as signaling molecules, helping direct everyday processes such as repair, metabolism, and energy

Medically reviewed by Lauren Okafor | MD , The Frank H Netter MD School of Medicine, Loyola University Medical Center on March 16th, 2026

Under conditions of low glucose, oxidative stress, or inflammation, mitochondria increase production of MOTS-C, which then: Enters the nucleus to modulate transcription of genes associated with antioxidant defenses, such as NRF2 targets