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PubMed PMID: 10885050

Genes found in fewer than 10 barcodes were not included in the following study

Treatment with pycnogenol resulted in a significant reduction in oxidative stress and a 32% increase in a measure of endothelial function

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Interestingly, these neuroprotective features have also been shown in humans, where post-menopausal women taking HRT, had fewer and smaller damaged areas after an ischemic event comparing to controls (non-HRT) (Gibson et al., 2006)