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Cycling Approach: Some practitioners implement protocols such as 12 weeks on, 4-8 weeks off to theoretically prevent receptor desensitization, reduce long-term costs, or provide physiological breaks

In lean C57BL/6J mice, chronic treatment with hGH led to a significant increase in body weight, becoming apparent by day 8

Sermorelin promotes pulsatile endogenous GH release via central GHRH signaling, producing systemic GH effects, including potential support for lean mass and recovery

Between sessions: daily topical GHK-Cu 1% serum (5 days on, 2 off)

Results depend on baseline B12 status