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Side effects are rare but may include mild irritation at the injection site

By suppressing the transcription factor ZEB1, miR-200b-3p reverses epithelialmesenchymal transition, induces mesenchymalepithelial transition, and modulates angiogenesis by targeting VEGF and epidermal growth factor receptor 2 (Wellner et al., 2009

[DOI] [PMC free article] [PubMed] [Google Scholar] 11.Canning P., Sorrell F., Bullock A.N

Unlike conventional cell death pathways such as necrosis and apoptosis, ferroptosis has distinctive features

For example, the general applications of adeno-associated virus-based gene therapy are hampered by pre-existing humoral immune responses against the viral vectors [350,351,352], which for some viral serotypes occur in up to 60% of the population because of early-life infections [353, 354]