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Those who initially used CPAP may be candidates for retesting and potential discontinuation under medical supervision
Frias JP, Nauck MA, Van J et al (2020) Efficacy and tolerability of tirzepatide, a dual glucose-dependent insulinotropic peptide and glucagon-like peptide-1 receptor agonist in patients with type 2 diabetes: a 12-week, randomized, double-blind, placebo-controlled study to evaluate different dose-escalation regimens
If the same weight-regain pattern holds for retatrutide, and the biology strongly suggests it will, then approval of retatrutide is not the end of a treatment decision but the beginning of a long-term management strategy
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Patients should seek immediate evaluation for symptoms such as difficulty breathing, facial or throat swelling, widespread rash, or significant skin changes that go beyond a typical injection site reaction
