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Bethel MA, Diaz R, Castellana N, et al

Simonetti O, Cirioni O, Goteri G, Lucarini G, Kamysz E, Kamysz W

2014;2014 doi: 10.1136/bcr-2013-201432

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Subsequently, nucleus translocation of PARP1-dependent AIF interacts with macrophage migration inhibitory factor (MIF) to format the AIF-MIF complex, which further induces the DNA breakage and ultimately results in parthanatos [140]