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Our data showed that AICAR (0.5 mmol/L) mimicked, while compound C (10 mol/L) abolished, the upregulating effects of metformin (1.0 mmol/L) on the protein levels of GLP-1R and p-PKA (Fig

These delivery platforms should incorporate stimuli-responsive release mechanisms, such as pH-sensitive or redox-sensitive components, to ensure precise spatiotemporal control of drug release within the TME