doi: 10.3390/genes15050617 122 MichelsonJRausserSPengAYuTSturmGTrumpffCet al
An enhanced potency is due to the markedly decreased binding of human Long-R3-IGF-I to IGF binding proteins which normally inhibit the biological actions of IGFs
This is supported by the finding that aging leads to more oxidation of the GSH and more damaged mtDNA in the mitochondria, which can be prevented by oral antioxidant administration
This comprehensive, multi-pathway approach is why many functional medicine practitioners consider this synergy a foundational element for patients learning how to live with long-term COVID
Common Add-ons Some clinics combine glutathione with Vitamin C, B12, or biotin for added skin and energy benefits
In relation to the GHK-Cu pathway, which supports collagen synthesis, extracellular matrix maintenance, and antioxidant defense, this genotype suggests that inflammatory signaling is likely functioning within expected physiological ranges, providing a supportive environment for regenerative processes