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FAQ Preliminary Phase 2 data shows Retatrutide achieved -24.2% weight loss in 48 weeks, while Mounjaro in Phase 3 showed -22.5% in 72 weeks

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When we followed a cohort of users managing weekly GLP-1 therapy for several months, the pattern became clear: people who escalated the dose slowly often reported steadier appetite control with fewer abrupt rebounds, while those who moved up faster or missed weeks reported more variable weeks and greater confusion about what to expect

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