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Retatrutide extends this further by incorporating GCGR activation, adding a third metabolic lever that directly increases energy expenditure

Yu J, Wang Y, Yan F, Zhang P, Li H, Zhao H, Yan C, Yan F, Ren X

Creatine is a compound our bodies make from the amino acids arginine, glycine, and methionine

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DIM (diindolylmethane) DIM is used to stimulate 2 hydroxylation (neutral estrogen pathway) via CYP1A1 and reduce expression of 16 hydroxylation (potential harmful estrogen pathway) through inhibiting CYP3a4