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Study limitations include small sample sizes, short durations, and lack of standardized fertility endpoints

However, WES enables the comprehensive analysis of approximate ~19,500 protein-coding genes and, depending on the library (e.g., Agilent SureSelect CRE V4), approximately 5,500 additional clinically relevant loci, including splice sites, untranslated regions, lncRNAs, pseudogenes, and regulatory elements

The fact that TMA and TMAO were detected in the normal diet group suggested that the amount of TMA or TMAO synthesized in our medaka model in response to L-carnitine administration was small

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