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Information sources We searched PubMed, Embase and Cochrane databases on 27 October 2021 for English-language studies

10.1016/j.bpobgyn.2016.05.003 79 LongC.FengH.DuanW.ChenX.ZhaoY.LanY.et al (2022)

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Ipamorelin is a synthetic pentapeptide studied as a selective agonist of the growth-hormone secretagogue receptor (GHS-R)

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This is analogous to how 5-Amino-1MQ works in metabolic research-rather than adding a new signal, it removes a brake on an existing one (NNMT inhibition preserves NAD+