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The blood-labyrinth-barrier (BLB), which includes a blood-endolymph barrier and a blood-perilymph barrier, consists of tight junctions between specialized epithelial cells in the labyrinth spaces (i.e., the vestibular and cochlear spaces)

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Cardiovascular outcome trials have further demonstrated that GLP-1 agonists like semaglutide reduce major adverse cardiac events in patients with established heart disease or diabetes