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Comment: Commenters requested that CMS provide additional information so that other interested parties are able to replicate Addendum J in its entirety

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Compound Name: 5-Amino-1MQ Chemical Classification: NNMT (Nicotinamide N-Methyltransferase) Inhibitor Chemical Name: 5-Amino-1-Methylquinolinium Appearance: White to off-white lyophilised powder Solubility: Typically soluble in bacteriostatic water or sterile research-grade diluents Research Category: Metabolic- and NAD-pathway research compound Common Research Areas: NAD-metabolism investigations NNMT-pathway research Mitochondrial-function studies Metabolic-regulation investigations Glucose- and insulin-related research Healthy-aging and cellular-energy research models Cellular-maintenance and physiological-resilience investigations For Laboratory and Research Purposes Only Not intended for human consumption or therapeutic use