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IV doses of 25-400 mcg/kg for safety studies Important: These are experimental doses used in animal studies and cannot be extrapolated to other species due to significant differences in metabolism, pharmacokinetics, receptor expression, peptide degradation rates, and tissue distribution patterns
Alternatively, PGC-1 may mediate the expression of motor proteins in spinal cord motoneurons and thus modulate movement disorders in an animal model of PD through the stimulation of the upstream promoter of the mitochondrial fusion-associated protein Mfn2 (Mou et al., 2021
Dosage and treatment protocols should always be determined by a qualified healthcare provider based on your individual health history and goals
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