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It is also used as an ointment for reducing the referred pain of sciatica but we should also be cautious of the toxic aspects and the potential risks accompanying its use [] Anacyclus pyrethrum (L.) An important medicinal herb used in traditional medicine and the roots are of great importance

reported that Asp and Asn in colon cancer cell lines could inhibit their activities by binding to LKB1 (encoding filament, threonine kinase, and direct phosphorylation of protein products to activate AMPK), thus inhibiting AMPK-mediated p53 activation