The GHRH receptor pathway CJC-1295 binds to GHRH receptors on somatotroph cells in the anterior pituitary gland
Hauber AB, Nguyen H, Posner J, Kalsekar I, Ruggles J
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66%-86%) is higher than those adapted to high-carnitine diets (i.e., regular red meat eaters
This preservation of pulsatility distinguishes CJC-1295 from exogenous GH administration, which suppresses endogenous GH pulsatility through negative feedback
A study in 73 healthy adolescents using 24-hour GH sampling found mean integrated GH concentrations of 3.8 ng/mL in mid-puberty compared with 1.1 ng/mL in young adults, a 3.5-fold difference [5]